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Genetic Collection Protocol

Launched by ARBOR RESEARCH COLLABORATIVE FOR HEALTH · Mar 8, 2022

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

ClinConnect Summary

The Genetic Collection Protocol is a study looking into liver diseases by collecting samples of blood or saliva from participants. The main goal is to gather and store DNA, which will be used for ongoing and future research related to these conditions. This study is currently recruiting participants, including children aged 1 to 9131 and their biological parents, to help advance our understanding of liver diseases.

To participate, children must have previously been part of specific studies (like PROBE, BASIC, LOGIC, or MITOHEP) and still be under care at the clinical site. Their biological parents can also take part if they haven't previously provided a DNA sample. Participants will only need to provide a sample once, and the process is straightforward. It's important to note that some individuals, such as those who have passed away or cannot be contacted, are not eligible for the study. This research is crucial for improving treatment and care for liver diseases in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • For Child Participants
  • 1. Previous enrollment in PROBE, BASIC, LOGIC, or MITOHEP
  • 2. Exited from one of the aforementioned studies.
  • 3. Consent for DNA sample collection obtained during enrollment during enrollment to one of the aforementioned studies but sample not previously collected.
  • 4. Still followed at the clinical site.
  • For Biological Parent Participants
  • 1. Biological parents of previously consented child participant without collection of a parental DNA biospecimen.
  • 2. Child still followed at the clinical site.
  • Exclusion Criteria:
  • For Child Participants
  • 1. Participant is deceased
  • 2. Participant exited from prior study due to violating eligibility criteria
  • 3. Participant cannot be contacted
  • For Biological Parent Participants
  • 1. Non-biological parent
  • 2. Child DNA was not previously collected and will not be collected in this study

About Arbor Research Collaborative For Health

Arbor Research Collaborative for Health is a non-profit research organization dedicated to improving health outcomes through innovative clinical research and data analysis. With a focus on advancing medical knowledge and patient care, Arbor Research collaborates with academic institutions, healthcare providers, and industry partners to conduct rigorous studies in various fields, including nephrology, infectious diseases, and health services research. Their commitment to scientific excellence and community engagement drives their mission to translate research findings into actionable solutions that enhance public health and inform healthcare policy.

Locations

Aurora, Colorado, United States

Seattle, Washington, United States

Indianapolis, Indiana, United States

Philadelphia, Pennsylvania, United States

Los Angeles, California, United States

Pittsburgh, Pennsylvania, United States

Toronto, Ontario, Canada

Cincinnati, Ohio, United States

Atlanta, Georgia, United States

Chicago, Illinois, United States

Salt Lake City, Utah, United States

San Francisco, California, United States

Houston, Texas, United States

Toronto, Ontario, Canada

Houston, Texas, United States

Patients applied

0 patients applied

Trial Officials

Ed Doo, MD

Study Director

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Averell Sherker, MD

Study Director

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

John Magee, MD

Principal Investigator

University of Michigan

Lisa Henn, PhD

Principal Investigator

Arbor Research Collaborative for Health

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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