SOMESThesia and ALIMentation

Launched by HOSPICES CIVILS DE LYON · Mar 8, 2022

Keywords

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• All subjects:
• • Person between 18 and 65 years
• • Person having given free, informed, express written consent
• • Person affiliated to a French social security system
• • Person with a body mass superior to 18 kg/m².
• • Person able to come once to the Institut Paul Bocuse
• Patients with head and neck cancer with chemotherapy:
• • - Patient diagnosed with squamous cell head and neck cancer with the following treatment regimen: Surgery + radiochemotherapy or radiochemotherapy alone
• Patients with head and neck cancer without chemotherapy:
• • - Patient diagnosed with squamous cell head and neck cancer with the following treatment regimen: Surgery + radiation therapy or radiation therapy alone
• Healthy volunteers :
• • Volunteer who is +/- 5 years of age relative to the patient to whom they are matched.
• • Volunteer of the same sex as the patient to whom they are matched
• • Volunteer with the same smoking status as the patient to whom they are matched
• • Volunteer who has not had cancer within 5 years at the time of inclusion
• • Volunteer with no current treatment that may affect taste and smell perception
• Exclusion Criteria:
• All subjects:
• • Person with a known food allergy/intolerance (lactose or milk protein) or unable to consume dairy or solid products (e.g., chocolate milk pudding, chocolate jelly)
• • Person with a known allergy to chili (or capsaicin)
• • Person with diagnosed total ageusia
• • Person with diagnosed total anosmia
• • Person who has used artificial feeding within 2 months prior to inclusion.
• • Person who has lost more than 10% of baseline weight in the 2 months prior to inclusion
• • Person deprived of liberty or under guardianship or trusteeship.
• • Pregnant or breastfeeding woman
• • Person deprived of liberty by a judicial or administrative decision
• • Person under guardianship or protection of vulnerable adults
• • Person with trismus (reduced jaw opening or limited jaw range of motion)
• • A person who is unable to extend his or her tongue
• • Person who has had surgery on the mobile tongue and/or base of the tongue
• • Person unable to swallow soft foods
• • Person who has had or is suspected of having had Corona Virus Disease (COVID)-19 within the last 6 months.
• Patients with head and neck cancer:
• • Patient receiving immunotherapy
• • Patient treated with surgery only.