Biological Variables Associated With the Response to Intensive Training in Athletes

Launched by UNIVERSITY HOSPITAL, MONTPELLIER · Mar 14, 2022

Keywords

ClinConnect Summary

This clinical trial is studying how different biological factors affect how athletes recover from muscle injuries after intensive training. Researchers want to understand why some athletes heal better than others, even when they are similar in age, physical activity, and medical history. They believe that both genetic and epigenetic factors—changes in how genes are expressed—play a role in how muscles respond to exercise and recover from damage. By identifying these factors, the study aims to improve training programs and recovery strategies for athletes.

To participate in this trial, you must be a senior male athlete aged between 40 and 60 who is currently following a muscle-building program aimed at improving your performance in middle-distance races. Participants will undergo training and various assessments, including muscle mass measurements, to help researchers understand how training impacts muscle recovery. It’s important to note that certain health conditions or the use of specific medications may prevent someone from joining the study. This research could lead to better approaches for muscle recovery and performance enhancement in athletes.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • Senior male athlete aged between 40 and 60 inclusive
• • Athlete following a program over a season of muscle building at CREPS, the objective of which is to improve their performance in a middle-distance race.
• Exclusion Criteria:
• • Subject having a contraindication to follow the complete muscle building program at CREPS with in particular a contraindication to the measurement of muscle mass by Magnetic Resonance Imaging
• • Subject presenting all criteria which can by themselves alter the function of the respiratory muscles such as chronic obstructive pulmonary disease, heart failure, systemic infection, neuromuscular pathology, psychiatric pathology, metabolic disorder.
• • Subjects with coagulopathy or thrombocytopenia.
• • Use of anabolic drugs to increase muscle mass
• • Subject suspected of doping
• • Subject allergic to xylocaine