Effect of Smoking and Periodontal Therapy on Salivary and Gingival Crevicular IL-17 and IL-35

Launched by GAZI UNIVERSITY · Mar 15, 2022

Keywords

ClinConnect Summary

Periodontal diseases are among the complex inflammatory diseases that are considered among the leading causes of tooth loss, mostly observed with multiple etiological factors. The complexity of periodontal disease is due to the presence of the biofilm and the accompanying host response together.

Smoking, which is considered as one of the risk factors in terms of periodontitis, is one of the most preventable risk factors that affect the periodonium with many different mechanisms. Smoking plays a role in the etiopathogenesis of periodontitis, with its physiological changes in gingival tissue...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • To be volunteer to participate in the study
• • To be over 18
• • Being systemically healthy
• • Having greater than or equal to 15 teeth out of 3rd molar teeth
• • To have localized or generalized periodontitis for the experimental group (clinical attachment loss in at least 6 surrounding areas and presence of greater than or equal to 5 mm periodontal pocket)
• • For Smoking group; more than 10 cigarettes a day for more than 5 years
• • For non-smokers; have not smoked for at least 3 years.
• Exclusion Criteria:
• • Have any systemic disease affecting periodontal condition
• • To receive periodontal treatment in the last 6 months
• • Use any medication that may affect the inflammatory process in the last 3 months
• • Use local or systemic antibiotics in the last 3 months
• • Pregnancy or lactation for female patients
• • Regular use of mouthwash