Quantification of Inspiratory Effort Through Nasal Pressure in Patients Undergoing Weaning From Invasive Mechanical Ventilation and Correlation With Clinical Outcomes

Launched by UNIVERSITY OF MODENA AND REGGIO EMILIA · Mar 7, 2022

Keywords

ClinConnect Summary

This clinical trial is studying how to better measure breathing effort in patients who are being taken off invasive mechanical ventilation (a machine that helps them breathe). The goal is to find a simple and non-invasive way to assess how much effort patients need to breathe after their breathing tube is removed. This is important because around 20% of patients may struggle and need to be put back on the machine, which can lead to longer hospital stays and increased risks. The researchers are exploring if measuring nasal pressure (the pressure at the nostrils) can accurately show how hard patients are working to breathe, which could help doctors identify those at higher risk of needing more support.

To be eligible for this trial, participants should be adults aged 18 and older who are candidates for having their breathing tube removed. However, individuals with certain conditions like neuromuscular diseases or a lower level of consciousness will not be included. If someone participates, they can expect to have their nasal pressure measured to help understand their breathing effort better, contributing to safer and more effective care for patients in similar situations.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • - candidates for endotracheal tube removal.
• Exclusion Criteria:
• • Age under 18
• • Pregnancy
• • Patient unable or unwilling to sign informed consent
• • Neuromuscular diseases
• • Patient with compromised neurological state (Glasgow Coma Scale (GCS) under 14/15)