Intrapleural Nebulization of Bupivacain to Reduce Postoperative Pain

Launched by ASSIUT UNIVERSITY · Mar 7, 2022

Keywords

ClinConnect Summary

This clinical trial is studying a new way to help manage pain after lung surgery, specifically video-assisted thoracic surgery (VATS). The trial is testing a method called intrapleural nebulization of bupivacaine, a local anesthetic that can help numb pain without the need for multiple injections. This method aims to reduce postoperative pain and improve recovery by using a fine mist of the medication, which can spread evenly and require less medicine overall.

To participate in the trial, patients should be between the ages of 18 and 80, scheduled for VATS surgery, and in generally good health (ASA class 1-3). However, those with allergies to local anesthetics, certain recent health issues, or kidney and liver problems may not be eligible. Participants can expect to receive the nebulized medication during their surgery and will be monitored for pain levels and recovery. This trial is currently recruiting participants and aims to find a safer and more effective way to manage pain after lung surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients that reach American socity of anesthesiologist class 1-3
• • Scheduled for VATS surgery under general anesthesia.
• Exclusion Criteria:
• • ● Allergy to local anesthetics
• • Patient with pleural inflammation due to recent pneumonia
• • Patients who are unable or unwilling to perform spirometer test
• • Renal dysfunction: (Elevated creatinine \> 2 mg\\dl)
• • Hepatic dysfunction: (Elevated hepatic enzymes three times above normal value)
• • History of addiction