Modeling TMS-induced Cortical Network Activity

Launched by MASSACHUSETTS GENERAL HOSPITAL · Mar 11, 2022

Keywords

ClinConnect Summary

This clinical trial is studying how different parts of the brain connect and communicate with each other in healthy individuals. Researchers will use a non-invasive technique called transcranial magnetic stimulation (TMS) to stimulate specific brain areas while also measuring brain activity with a method called electroencephalography (EEG). By doing this, they hope to learn how quickly signals travel between brain regions and how stimulating two areas at once might affect their connection.

To participate in this study, you need to be a healthy adult between the ages of 18 and 75, with normal hearing and vision, and able to give your consent to join the trial. However, certain conditions would prevent you from participating, such as having metal implants in your body, a history of seizures, or certain medical devices like pacemakers. If you join the study, you can expect a safe and non-invasive experience where your brain's activity is monitored while researchers explore how it functions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Healthy
• • Normal hearing and (corrected) vision
• • Able to understand and give informed consent
• Exclusion Criteria:
• • Metal in the body (rods, plates, screws, shrapnel, dentures, IUD)
• • Metallic particles in the eye
• • Surgical clips in the head or previous neurosurgery
• • Cardiac pacemaker or pacemaker wires
• • Neurostimulators
• • Implanted pumps
• • Any magnetic particles in the body
• • Cochlear implants
• • Prosthetic heart valves
• • Epilepsy or any other type of seizure history
• • Significant claustrophobia
• • Meniere's disease
• • Pregnancy or breast-feeding
• • Diagnoses or medications (neurological or psychiatric) influencing brain function
• • History of, or current, substance abuse
• • History of developmental disorders (e.g., dyslexia)
• • Failure to perform the behavioral tasks
• • Prisoners