Total Versus Robotic Assisted Unicompartmental Knee Replacement

Launched by NHS LOTHIAN · Mar 11, 2022

Keywords

ClinConnect Summary

This clinical trial is looking at two different types of knee surgery for patients with severe osteoarthritis (OA) in the inner part of the knee. One option is a traditional surgery called total knee arthroplasty (TKA), and the other is a newer, less invasive technique called robotic-assisted unicompartmental knee arthroplasty (UKA). The study aims to see which method helps patients recover better and whether there are differences in costs between the two types of surgery.

To participate in this trial, you need to be between 50 and 75 years old and have been recommended for knee surgery due to advanced OA. You should have a healthy anterior cruciate ligament and good quality cartilage on the outer side of your knee. If you have certain other health conditions or previous knee surgeries, you might not be eligible. If you join the study, you’ll be monitored during your recovery and asked to complete some questionnaires to help researchers understand the outcomes of each surgery. Your participation could contribute to important insights about knee surgeries and their effectiveness!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Listed for elective primary TKA for end stage medial compartment osteoarthritis
• • Intact anterior cruciate ligament
• • Full thickness and good quality lateral cartilage
• • Correctable intra-articular varus deformity and intact medial collateral ligament
• • American Society of Anesthesiologists (ASA) grades 1 and 2
• • Male or female, age 50 - 75 at the time of listing for surgery
• • Suitable candidate for a cruciate retaining TKA (Triathlon prosthesis) and a UKA
• Exclusion Criteria:
• • Varus deformity of \> 20 degrees
• • Fixed flexion of \>10 degrees
• • Patient is unable to comply with the study protocol (incl. refusal for CT scan) or functional assessments
• • Female participants who are pregnant, lactating or planning pregnancy during the course of the study
• • Requires patella resurfacing or lateral compartment has significant OA
• • Inability to understand the patient information for the study, provide written informed consent or answer study questionnaires for cognitive or language reasons
• • Inflammatory disorder e.g. rheumatoid arthritis
• • Symptomatic foot, hip or spine pathology
• • Prior surgery (other than arthroscopy) or septic arthritis of the knee
• • Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study,