Fully Automated High-Throughput Quantitative MRI of the Liver
Launched by UNIVERSITY OF WISCONSIN, MADISON · Mar 15, 2022
Trial Information
Current as of July 22, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is exploring a new method of using magnetic resonance imaging (MRI) to take better pictures of the liver. The goal is to see if this automated MRI can help improve the way we look at liver health, especially for people with known or suspected liver disease, those who might have too much iron in their liver, or even healthy adults. Participants will be involved in the study for just one day.
To join the trial, you need to be at least 18 years old, or 7 years old if you’re part of a specific group looking at liver conditions. However, you cannot participate if you have certain medical devices like a pacemaker, if you have claustrophobia (fear of tight spaces), or if you are pregnant or trying to become pregnant. During the visit, participants will undergo an MRI, which is a painless test that uses magnets and radio waves to take pictures of the inside of the body. This study is currently looking for volunteers, so if you're interested and meet the criteria, you could help us learn more about liver health.
Gender
ALL
Eligibility criteria
- • Eligibility Criteria for Substudies 1, 2, 4, 5
- Inclusion Criteria:
- • Age 18 years or older
- Exclusion Criteria:
- • Patients with contraindication to MRI (e.g. pacemaker, contraindicated metallic implants, claustrophobia, etc)
- • Pregnant or trying to become pregnant (as determined by self-report during MRI safety screening)
- • Eligibility Criteria for Substudy 3
- Inclusion Criteria:
- • Age 7 years or older
- * One of:
- • Known or suspected liver iron overload
- • Known or suspected elevated liver fat
- Exclusion Criteria:
- • Patients with contraindication to MRI (e.g. pacemaker, contraindicated metallic implants, claustrophobia, etc)
- • Sedation required for MRI
- • Pregnant or trying to become pregnant (as determined by self-report during MRI safety screening)
- • Eligibility Criteria for Substudy 6
- Inclusion Criteria:
- • Age 7 years or older
- • Scheduled for a clinical abdominal MRI exam
- Exclusion Criteria:
- • Patients with contraindication to MRI (e.g. pacemaker, contraindicated metallic implants, claustrophobia, etc)
- • Sedation required for MRI
- • Pregnant or trying to become pregnant (as determined by self-report during MRI safety screening)
About University Of Wisconsin, Madison
The University of Wisconsin-Madison is a leading research institution renowned for its commitment to advancing healthcare through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, the university leverages its extensive resources, including cutting-edge facilities and a diverse pool of expert researchers, to conduct rigorous studies that address critical health challenges. The institution's focus on translating research findings into practical applications fosters the development of new treatments and interventions, ultimately contributing to improved patient outcomes and public health initiatives. As a sponsor of clinical trials, the University of Wisconsin-Madison is dedicated to upholding the highest ethical standards and ensuring participant safety throughout the research process.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Madison, Wisconsin, United States
Patients applied
Trial Officials
Scott Reeder, MD, PhD
Principal Investigator
University of Wisconsin, Madison
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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