Application of 3D MR Neurogram for Intraparotid Facial Nerves Evaluation
Launched by CHINESE UNIVERSITY OF HONG KONG · Mar 15, 2022
Trial Information
Current as of July 01, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a new imaging technique called 3D MR Neurogram, which helps doctors see the tiny branches of facial nerves near parotid tumors better than traditional methods. The parotid gland is located near the jaw and can develop both benign (non-cancerous) and malignant (cancerous) tumors. When surgeons remove these tumors, there is a risk of damaging the facial nerves, which can lead to temporary or permanent facial weakness. The goal of this trial is to see if using this advanced MRI technique can help doctors visualize the nerves more clearly during surgery, potentially reducing the risk of nerve injury.
To participate in this study, patients aged 65 and older who have been diagnosed with a parotid tumor through other imaging tests (like ultrasound or CT scans) may be eligible. However, individuals with certain conditions that prevent them from having an MRI or those who are unable to provide consent will not be included. Participants will undergo MRI scans to help map the nerves before their surgery. This could lead to safer surgical procedures and better outcomes for patients with parotid tumors.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Consecutive patients with parotid tumour diagnosed on other imaging modalities (such as ultrasonography or computed tomography), with or without cytological diagnosis from fine needle aspiration, will be recruited from the ear, nose and throat specialty clinic.
- Exclusion Criteria:
- • Patients who are contraindicated to magnetic resonance imaging (such as due to underlying MRI incompatible metallic implants)
- • Patient who are contraindicated to MRI contrast agents (such as advanced renal failure or previous severe allergic reaction)
- • Patients who cannot cooperate for MRI scanning.
- • Patients show are unable to provide informed consent.
About Chinese University Of Hong Kong
The Chinese University of Hong Kong (CUHK) is a prestigious research institution renowned for its commitment to advancing medical science and improving healthcare outcomes. As a clinical trial sponsor, CUHK leverages its extensive academic resources and interdisciplinary expertise to conduct innovative research that addresses critical health challenges. The university fosters collaboration among leading researchers, healthcare professionals, and industry partners, ensuring rigorous study design and implementation. CUHK is dedicated to upholding the highest ethical standards in clinical research, with a focus on translating findings into tangible benefits for patients and the broader community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Hong Kong, , Hong Kong
Patients applied
Trial Officials
Ho Sang Leung, MBBS (HK)
Principal Investigator
Department of Imaging and Interventional Radiology, Prince of Wales Hospital
Chiu Wing WInnie Chu, MD, FHKCR
Study Director
Department of Imaging and Interventional Radiology, Prince of Wales Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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