Lymphoedema and Nocturia/Nocturnal Polyuria After Pelvic LND for Urogenital Cancer

Launched by UNIVERSITAIRE ZIEKENHUIZEN KU LEUVEN · Mar 17, 2022

Keywords

ClinConnect Summary

This clinical trial is studying the effects of pelvic lymph node dissection (a type of surgery) on patients with urogenital cancer, particularly focusing on how it may lead to conditions like leg swelling (lymphoedema) and issues with nighttime urination (nocturia and nocturnal polyuria). Researchers want to understand how common these problems are after surgery and which methods are best for detecting early signs of leg swelling. This is important because these conditions can affect a person’s quality of life, and the impact they have on treatment decisions isn't well understood.

To participate in the study, you should be between 65 and 74 years old and have non-metastatic (not spread) urogenital cancer, such as prostate or bladder cancer. You also need to be scheduled for a specific type of surgery related to your cancer. Before joining, you’ll need to give your written consent. If you have certain medical conditions, like signs of advanced vein issues or a history of previous lymph node surgeries, you may not be eligible. Participants will help researchers gather valuable information that could improve care for future patients facing similar challenges.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Non-metastatic urogenital cancer (i.e. prostate cancer or bladder cancer)
• • Planned transperitoneal pelvic lymph node dissection or salvage lymph node dissection
• • Before inclusion, written informed consent must be given according to ICH/GCP, and national/local regulations.
• Exclusion Criteria:
• • Radiological evidence of metastatic disease based on pelvic CT/MRI and bone scan
• • Clinical signs of chronic venous insufficiency (CEAP C3-C6)
• • History of lymph node dissection/ radiotherapy at the level of the pelvis or groin