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Search / Trial NCT05306054

Physical Activity, Knee Joint Loading and Joint Health

Launched by UNIVERSITY OF BATH · Mar 30, 2022

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Physical Activity Knee Joint Loading Cumulative Load Biomarkers Musculoskeletal Modelling Patient Reported Outcomes

ClinConnect Summary

This clinical trial is studying how physical activity affects knee health after surgery for an anterior cruciate ligament (ACL) injury. The researchers want to see if spending more time doing moderate to vigorous exercise can influence the health of cartilage, which is the tissue that helps cushion the joints. This study is open to people aged 18 to 39 who have had ACL reconstruction surgery within the last 1 to 7 years, and who have completed their rehabilitation and received clearance from a healthcare provider to participate in physical activities.

Participants in this study will be asked to attend the University of Bath and may undergo assessments related to their physical activity and knee health. It's important to note that some individuals may not be eligible, especially if they have had other significant knee injuries, certain health conditions, or if they are outside the specified age range. This trial aims to gather valuable information that could help improve recovery and joint health for those recovering from ACL injuries.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. 18-39 years old (i.e., ≥18 and \<40 years old)
  • 2. Had an anterior cruciate ligament injury and reconstruction 1-7 years ago (i.e., ≥1 and ≤7 years ago)
  • 3. Can have sustained damage to meniscus or cartilage, or sustained bone bruising when injured anterior cruciate ligament
  • 4. Can participate regardless of the type of reconstruction surgery and if undergone meniscectomy
  • 5. Completed anterior cruciate ligament reconstruction rehabilitation and either a surgeon, doctor or physiotherapist has provided clearance to participate in physical activity
  • 6. Be able to attend the University of Bath within 2 hours of waking
  • Exclusion Criteria:
  • 1. Had another significant knee injury either before, at the same time, or after the anterior cruciate ligament injury (e.g., if they injured another ligament in their knee or had a fracture or dislocation)
  • 2. Injured the anterior cruciate ligament in both knees (bilateral ACL injury)
  • 3. Have/are experiencing a musculoskeletal, cardiovascular, respiratory, immune, metabolic or neurological disease or disorder
  • 4. Under 18 or over 39 (i.e., ≥40) years of age
  • 5. Body Mass Index ≥40 kg/m²
  • 6. Pregnancy
  • 7. Positive responses to the Physical Activity Readiness Questionnaire (aside from any involved knee joint issues)

About University Of Bath

The University of Bath is a leading UK institution recognized for its commitment to academic excellence and innovative research. With a strong focus on health and well-being, the university conducts clinical trials that aim to advance medical knowledge and improve patient outcomes. Leveraging a multidisciplinary approach, the University of Bath collaborates with various stakeholders, including healthcare professionals and industry partners, to ensure the integrity and efficacy of its research initiatives. Through its state-of-the-art facilities and expertise, the university is dedicated to contributing valuable insights to the scientific community and enhancing the quality of healthcare.

Locations

Bath, , United Kingdom

Patients applied

0 patients applied

Trial Officials

Karl Morgan, MSc

Principal Investigator

University of Bath

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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