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Search / Trial NCT05311774

Efficacy of Duloxetine in Conjunction With Tramadol for Chronic Cancer Pain

Launched by ASSIUT UNIVERSITY · Apr 3, 2022

Trial Information

Current as of June 27, 2025

Recruiting

Keywords

Duloxetine Tramadol Cancer Pain

ClinConnect Summary

This clinical trial is studying the effectiveness of combining two medications, Duloxetine and Tramadol, to help manage chronic pain caused by cancer. Chronic cancer pain can be very challenging to treat, especially with standard pain medications, which often come with unpleasant side effects. Tramadol is a pain reliever that works differently than traditional opioids, and Duloxetine is usually used as an antidepressant but also helps with certain types of pain, especially nerve pain. By using both medications together, the trial aims to see if this combination provides better pain relief for patients.

To be eligible for this study, participants must be between the ages of 20 and 70 and have cancer-related pain without currently taking any pain medications. If you join the trial, you’ll receive these medications and be monitored by healthcare professionals to assess how well they work for your pain. It's important to know that this study is currently recruiting participants, so if you or someone you know is dealing with cancer pain, this might be an opportunity to explore new treatment options.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients with cancer pain
  • 1. age from 20-70 years old.
  • 2. not receiving any type of analgesia before (opioid naïve, no adjuvants).
  • Exclusion Criteria:
  • 1. Difficult to be assessed for pain.
  • 2. Any contraindication for duloxetine or tramadol.

About Assiut University

Assiut University, a prominent academic institution located in Egypt, is dedicated to advancing medical research and clinical trials that enhance healthcare outcomes. With a strong emphasis on innovation and collaboration, the university engages in a wide array of clinical studies across various disciplines, aiming to contribute valuable insights into disease prevention, diagnosis, and treatment. Assiut University's commitment to ethical research practices and rigorous scientific methodology ensures the integrity and reliability of its clinical trials, ultimately benefiting both the local community and the global medical landscape.

Locations

Assiut, , Egypt

Patients applied

0 patients applied

Trial Officials

khaled M Fares, MD

Study Director

Assiut University

Ahmad M Abd EL Rahman, MD

Study Director

Assiut University

Diab F Hetta, MD

Study Director

Assiut University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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