Nutritional Support During Induction Therapy for Esophageal Cancer

Launched by MEHDI QIABI · Mar 29, 2022

Keywords

ClinConnect Summary

This clinical trial, titled "Nutritional Support During Induction Therapy for Esophageal Cancer," is exploring the best way to provide nutrition for patients with esophageal cancer undergoing treatment. When patients receive chemotherapy and radiation therapy, they often struggle to eat because the cancer can block their food pipe. One common approach is to insert a feeding tube directly into the stomach to help ensure they get enough calories. However, these tubes can sometimes cause problems, like infections or getting blocked, which might delay treatment or require additional medical procedures. This trial aims to compare the outcomes of using feeding tubes versus other methods to see which is more effective and safer for patients.

To participate in this trial, you must be an adult diagnosed with esophageal or gastroesophageal junction cancer and eligible for specific treatments. The trial is open to those aged 65 and older who can undergo the required therapy. If you join, you will be randomly assigned to one of the treatment approaches, and your health will be monitored closely throughout the study. It's important to know that this trial is currently recruiting participants, and your involvement could help improve care for future patients facing similar challenges.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adult patient
• • Non-cervical biopsy-proven esophageal or gastroesophageal junction (Siewert I or II) cancer
• • Patient eligible for induction therapy then esophagectomy (stage Ib to III)
• Exclusion Criteria:
• • Impossibility to pass an endoscope beyond the tumour
• • metastatic disease
• • early-stage disease with either upfront esophagectomy or endoscopic resection planned
• • patient refusal of the feeding tube
• • inability to swallow their pill
• • inability to tolerate a full fluid diet