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Search / Trial NCT05317637

Cardiopulmonary Outcomes in Osteogenesis Imperfecta: BBD7708

Launched by BAYLOR COLLEGE OF MEDICINE · Mar 31, 2022

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial, called "Cardiopulmonary Outcomes in Osteogenesis Imperfecta: BBD7708," is studying how a condition known as osteogenesis imperfecta (OI) affects the lungs and overall breathing in people with this disorder. OI is often called "brittle bone disease" because it causes bones to be fragile, but it also impacts other connective tissues in the body, including those in the lungs. Since breathing problems can be a serious issue for individuals with OI, researchers want to learn more about why these lung issues occur and how they relate to the condition.

To participate in this trial, you need to be at least 18 years old and have a diagnosis of OI, either through medical evaluation or genetic testing. The study is open to both men and women of all backgrounds. If you join the trial, you will work with a team of healthcare professionals who will monitor your health and help gather important information about how OI affects your lungs. It's important to know that if you have a recent respiratory illness or other serious lung conditions, you may not be eligible to participate. This trial is currently recruiting participants, and your involvement could help improve understanding and treatment options for others with this condition.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Individuals who are able to give informed consent or have a legally authorized representative capable of giving consent on the subject's behalf
  • Individuals ages 18 and older of all races and sexes
  • Individuals who have been diagnosed with OI clinically and/or genetically
  • Exclusion Criteria:
  • Individuals diagnosed with respiratory illness within 6 weeks of enrollment or undergoing diagnostic studies for an active illness.
  • Individuals with other skeletal dysplasia or genetic diagnosis
  • Individuals diagnosed with cardiopulmonary comorbidities that affect lung compliance

About Baylor College Of Medicine

Baylor College of Medicine is a leading academic institution dedicated to advancing health through innovative research, education, and clinical care. Located in Houston, Texas, it is renowned for its commitment to excellence in medical education and translational research, fostering collaborations that bridge laboratory discoveries with clinical application. As a clinical trial sponsor, Baylor College of Medicine leverages its robust infrastructure, interdisciplinary expertise, and access to diverse patient populations to conduct cutting-edge clinical studies aimed at improving patient outcomes and enhancing therapeutic approaches across a wide range of medical conditions.

Locations

New York, New York, United States

Los Angeles, California, United States

Los Angeles, California, United States

Baltimore, Maryland, United States

Patients applied

0 patients applied

Trial Officials

Vernon Sutton, MD

Principal Investigator

Baylor College of Medicine

Kathleen Raggio

Study Chair

Hospital for Special Surgery, New York

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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