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Search / Trial NCT05321641

Evaluation Of A Mobile Messaging Service In Improving Adherence Of Anti-Seizure Medications

Launched by KEMRI-WELLCOME TRUST COLLABORATIVE RESEARCH PROGRAM · Apr 4, 2022

Trial Information

Current as of July 22, 2025

Unknown status

Keywords

ClinConnect Summary

Improved outcomes for epilepsy treatment depend on a continuous supply and daily adherence to anti-seizure medications (ASMs). In Kilifi County, the treatment gap which includes both the diagnostic and adherence gap, is greater than 70% and investigators have found interruption of supply of ASMs to peripheral clinics, distance from clinic and lack of availability of ASMs, to be barriers to adherence. In Nairobi County, factors such as environment hazards, lack of social amenities and correlates of poverty are preponderant in slums, but the prevalence of epilepsy has not been studied in such...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Children or adults with a diagnosis of epilepsy ascertained by a clinician at the epilepsy clinic
  • Taking anti-seizure medications at the time of the study
  • Living within an area defined as the Kilifi Health Demographic Surveillance System, or the Nairobi Urban Health and Demographic Surveillance System at the time of the study or attending the epilepsy clinic in Kilifi or a KAWE-led clinic in Nairobi
  • Able to give written informed consent or assent in addition to parental consent (if aged between 13 and 17 years old) to participate in the study either by themselves or in the presence of an independent witness
  • Exclusion Criteria:
  • Have intellectual disability
  • Do not have access to basic mobile phones
  • Are currently enrolled in ongoing interventions aimed at improving their health care

About Kemri Wellcome Trust Collaborative Research Program

The Kemri-Wellcome Trust Collaborative Research Programme (KWTRP) is a leading clinical research organization based in Kenya, dedicated to advancing global health through innovative research and collaboration. Established as a partnership between the Kenya Medical Research Institute (KEMRI) and the Wellcome Trust, KWTRP focuses on addressing pressing health challenges, particularly infectious diseases, by conducting high-quality clinical trials and epidemiological studies. The program emphasizes capacity building, training, and community engagement, fostering a multidisciplinary approach that integrates science, health policy, and practice to improve health outcomes in Africa and beyond.

Locations

Kilifi, , Kenya

Patients applied

0 patients applied

Trial Officials

Charles R Newton, MD

Study Director

KEMRI-Wellcome Trust Collaborative Research Program

Symon M Kariuki, DPhil

Principal Investigator

KEMRI-Wellcome Trust Collaborative Research Program

Arjune Sen, PhD

Principal Investigator

University of Oxford

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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