Tracking of Upper Limb Sensory and Motor Recovery in Asian Stroke Survivors

Launched by TAN TOCK SENG HOSPITAL · Apr 10, 2022

Keywords

ClinConnect Summary

This clinical trial is studying how stroke survivors in Singapore recover the use of their arms after experiencing a stroke. The researchers want to understand the different stages of recovery in Asian adults so they can improve rehabilitation methods and help patients regain their daily living skills. They are currently looking for participants who are Asian, aged between 21 and 90, and have had their first confirmed stroke within the last eight weeks. Participants should also have a certain level of cognitive ability, as measured by a simple test.

If you or someone you know meets these criteria and decides to join the study, you can expect to be part of a group that will help researchers track how well the upper limbs recover over time. It's important to note that certain health conditions or previous strokes may disqualify someone from participating. This study aims to provide valuable insights that could lead to better rehabilitation practices for stroke survivors in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Stroke confirmed by neurologists, neurosurgeons and brain imaging (CT, CT angiogram, MRI, MR angiogram)
• • 2. First ever confirmed stroke
• • 3. Asian ethnicity
• • 4. Age 21-90 years
• • 5. Montreal Cognitive Assessment (MOCA) scores 21/30 and above
• • 6. Admission to rehabilitation ward is within 8 weeks of stroke onset
• Exclusion Criteria:
• • 1. Recurrent stroke or transient ischaemic attack (TIA)
• • 2. Upper limb impairment not related to stroke: e.g., subarachnoid haemorrhage, traumatic brain injury or brain tumours
• • 3. Bilateral upper limb impairment.
• • 4. Uncontrolled medical conditions such as hypertension, hypotension, diabetes mellitus, unstable angina, cardiac failure or sepsis will be excluded.
• • 5. Active fractures or arthritis of upper limb joints/bones
• • 6. Visual Analogue Scale (VAS) pain \> 5/10
• • 7. MOCA \< 21/30
• • 8. Severe behavioural disturbance or agitation or epilepsy or untreated depression
• • 9. Life expectancy \< 6 months
• • 10. End organ failures on replacements (renal dialysis or renal replacement therapies)
• • 11. Minimally responsive or unresponsive awareness (vegetative) states
• • 12. Pregnancy or lactation states
• • 13. Admission to rehab ward later than 8 weeks post-stroke
• • 14. (For TMS assessments only) History of epilepsy or seizures, or cranial surgeries, or have metal implants in body or head, or have implanted electronics, or have metallic valve, or skull fracture or brain injury, or head or brain surgeries.