Patient Derived Preclinical Models

Launched by MAYO CLINIC · Apr 5, 2022

Keywords

ClinConnect Summary

This clinical trial is focused on collecting tumor samples from patients with cancer to better understand the disease and improve treatment options in the future. By gathering tissue from tumors, as well as normal tissues when available, and blood samples, researchers hope to develop new ways to treat cancer more effectively. This study is a collaborative effort aimed at advancing cancer research.

To be considered for this trial, participants need to be at least 18 years old and must be in good health enough to undergo a standard biopsy or surgery to collect the tissue. However, patients with certain medical conditions or those who cannot safely provide informed consent may not be eligible. If you join this study, you can expect to have a biopsy that is assessed to ensure it's safe for you, and your participation will contribute to important cancer research that could help improve future outcomes for patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 18 years of age and older
• • Patient is a good medical candidate for a standard of care or research biopsy or surgical procedure to obtain tissue
• Exclusion Criteria:
• • Uncontrolled concurrent illness including psychiatric illness, or situations that would limit compliance with the study requirements or the ability to willingly give written informed consent
• • Institutionalized or incarcerated patients
• • Inaccessible tumor for biopsy or patient does not have tumor tissue available for research use
• • Biopsy must not be considered more than minimal risk to the patient.
• * Have a contraindication to percutaneous biopsy including:
• • 1. Significant coagulopathy that cannot be adequately corrected.
• • 2. Severely compromised cardiopulmonary function or hemodynamic instability.
• • 3. Lack of a safe pathway to the lesion per the interventional radiologist.
• • 4. Inability of the patient to cooperate with, or to be positioned for, the procedure.