Improvement in Glycemic Response After Bariatric Surgery

Launched by WEIZMANN INSTITUTE OF SCIENCE · Apr 5, 2022

Keywords

ClinConnect Summary

This clinical trial is looking at how certain bacteria in our gut, known as microbiota, affect blood sugar levels after patients undergo bariatric surgery, which is a type of weight-loss surgery. The researchers want to understand how these changes in gut bacteria can improve glycemic response, or how well the body manages blood sugar, after the surgery.

To be a part of this study, you need to be between 18 and 70 years old and scheduled for bariatric surgery or gallbladder removal surgery. However, you cannot participate if you have had previous bariatric surgery, have type 1 diabetes, or have taken certain medications like antibiotics or probiotics in the last three months. If you join the trial, you will help researchers learn more about the relationship between gut bacteria and blood sugar changes, which could lead to better outcomes for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • candidates of bariatric surgery or cholecystectomy
• • age 18-70
• • male/female
• Exclusion Criteria:
• • previous bariatric surgery
• • type 1 diabetes
• • antibiotic treatment 3 months prior to the study
• • probiotic treatment 3 months prior to the study
• • chronic disease - gastrointestinal disease, malignancy, psychiatric disorder, endocrinologic disorders
• • any pathologic findings during endoscopy
• • participants who will suffer from a post-operation complication