Effect of Protein, Mobility Therapy and Electric Stimulation on Recovery in Older ICU Survivors

Launched by UNIVERSITY OF MARYLAND, BALTIMORE · Apr 6, 2022

Keywords

ClinConnect Summary

This clinical trial is studying how a combination of physical therapy, high-protein nutrition, and electric stimulation can help older patients recover after being in the Intensive Care Unit (ICU). Many older patients who survive critical illness often experience weakness and difficulties moving because of their illness and other health issues. The goal of this trial is to see if these combined treatments can improve their strength and overall well-being. Researchers will also look at how this recovery relates to inflammation in the body.

To participate in this trial, individuals need to be at least 60 years old, have spent at least two weeks in the ICU, and be able to follow simple commands in English. They should be able to perform physical therapy and have been moderately independent before their ICU stay. Participants will receive the combination treatment and be monitored for improvements in their physical abilities and health. This study is not yet recruiting participants, but it aims to provide valuable insights into how to support recovery for older adults after critical illnesses.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. LTACH admission within 72 hours
• • 2. Age ≥ 60 years old
• • 3. Prior ICU stay ≥ 2 weeks
• • 4. Able to follow commands in English
• • 5. Pre-ICU Barthel Index ≥ 70
• • 6. Able to give consent
• • 7. Able to perform physical therapy
• • 8. All four limbs intact and mobile prior to LTACH admission
• Exclusion Criteria:
• • 1. Acute kidney injury with a glomerular filtration rate \<15 ml/min
• • 2. Diagnosis of severe organ dysfunction including end stage liver disease or cirrhosis
• • 3. Diagnosis of active cancer
• • 4. Severe functional impairment or physical impairment to rehabilitation
• • 5. Liver function tests \>2.5x normal limits
• • 6. Chronic dementia or cognitive impairment