Project 2: ACHIEVE- HF

Launched by HENRY FORD HEALTH SYSTEM · Apr 8, 2022

Keywords

ClinConnect Summary

The ACHIEVE-HF trial is part of a larger effort called ACHIEVE GREATER, aimed at improving heart health and reducing health inequalities, especially for Black individuals living in Detroit and Cleveland. This specific study focuses on heart failure and high blood pressure, two conditions that can significantly affect health. The goal is to help participants manage these conditions better through support from Community Health Workers, who will guide them in following a proven health program.

To be eligible for this study, participants need to be at least 18 years old, self-identify as Black or African American, and live in the Detroit area. They should also have high blood pressure or other related health issues, such as diabetes or kidney disease. Unfortunately, individuals with a history of heart failure or severe uncontrolled diabetes cannot participate. If you join the study, you can expect to receive personalized support and information to help manage your heart health effectively. This trial not only aims to improve individual health but also hopes to make a broader impact on community health disparities.

Gender

ALL

Eligibility criteria

• Inclusion:
• In order to be eligible to participate in this study, an individual must meet all of the following criteria:
• • 1. Detroit-area resident (defined as those who attended a Detroit-area community event)
• • 2. ≥18 years of age
• 3. At least one of the following:
• • A) Screening systolic BP ≥ 140 and/or diastolic BP ≥ 90 mm Hg OR
• B) Screening BP 130-139 mm Hg plus ≥1 additional HF risk factors:
• • i. Diabetes (HbA1c ≥ 6.5%) ii. CKD stage 3(i.e. eGFR 30-60 mL/min/m2) OR C) Treated (1-2 antihypertensive medications) stage 1 HTN (systolic BP 130-139 and/or diastolic BP 80-89) with or without \>1 additional HF risk factors OR
• D) Treated stage 1 HTN w/ systolic BP 120-129 with additional HF risk factors:
• • i. Diabetes (HbA1c ≥ 6.5%) ii. CKD stage 3(i.e. eGFR 30-60 mL/min/m2)
• Exclusion Criteria:
• An individual who meets any of the following criteria will be excluded from participation in this study:
• • 1. Previous diagnosis of HF
• • 2. Uncontrolled diabetes (HbA1C ≥8.0% from SOC screening labs)
• • 3. Chronic use of insulin or \>1 anti-diabetic medication
• • 4. Self-reported pregnancy (or planning to become pregnant in the next year)
• • 5. Severely uncontrolled BP at screening visits (SBP ≥180 mm Hg and/or diastolic BP ≥110 mmHg)
• • 6. Point of care (POC) BNP measurement ≥400 ng/L. If POC BNP was not obtained, then NTproBNP ≥ 1000 ng/L from screening labs will be excluded.
• • 7. eGFR \<45 ml/min/sq-m on SOC screening labs