Perioperative Longitudinal Study of Complications and Long-term Outcomes

Launched by UMC UTRECHT · Apr 8, 2022

Keywords

ClinConnect Summary

The Perioperative Longitudinal Study of Complications and Long-term Outcomes (PLUTO) is a clinical trial designed to learn more about the complications that can occur after certain surgeries and how to improve recovery. The study focuses on patients who are having elective surgeries that are considered to be of intermediate to high risk, particularly surgeries involving the gastrointestinal tract or blood vessels. Participants must be between 65 and 74 years old and able to provide informed consent. The trial will not include those under 18, those needing emergency surgery, or those with severe anemia.

During the study, participants will receive daily check-ups from dedicated medical staff for at least a week after their surgery. These visits will help monitor any complications, such as infections or heart issues, and will include simple tests and blood samples. The information gathered will help researchers understand how to better predict and manage postoperative complications, ultimately aiming to improve patient outcomes and quality of life after surgery. This research is important because it may lead to new ways to identify problems early and help patients recover more effectively.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • - Undergoing an elective, high-risk gastro-intestinal or vascular procedure, or intermediate risk procedure (including gynaecological, orthopaedic and head and neck surgery) if the procedure includes a laparotomy and/or is associated with a scheduled hospital length of stay ≥ 5 days.
• Exclusion Criteria:
• • \< 18 years of age
• • Emergency surgery
• • Severe anaemia (Hb \< 4.5 mmol/L)
• • Unable to provide informed consent