ClinConnect ClinConnect Logo
Search / Trial NCT05331456

Alveolar Cleft Repair Using Osteoinductive Ceramics

Launched by UMC UTRECHT · Apr 11, 2022

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Cleft Palate Cleft Lip Alveolar Cleft Calcium Phosphate Ceramics Bone Graft

ClinConnect Summary

This clinical trial is studying a new way to close the gaps in the upper jaw (alveolar clefts) in children who have a condition known as unilateral cleft lip and palate. The researchers want to compare two methods: one uses bone taken from the patient’s own body, while the other uses a special type of ceramic putty that helps the bone grow. This trial is currently looking for participants, specifically children aged between 2 and 4 years old who have a unilateral alveolar cleft and are ready for surgery to close it.

Eligible participants will take part in a study to see which method works better for repairing the cleft. Those who join the trial can expect to receive care from dental and medical teams throughout the process. It's important to note that children with cleft lip and palate caused by certain syndromes won’t be included in this study. This trial aims to find the best way to help these children and improve their dental health and quality of life.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • unilateral alveolar cleft, early secondary alveolar cleft closure
  • Exclusion Criteria:
  • cleft lip and palate in a syndromic context

About Umc Utrecht

UMC Utrecht is a leading academic medical center in the Netherlands, renowned for its commitment to innovative research and high-quality patient care. As a prominent sponsor of clinical trials, UMC Utrecht leverages its extensive expertise in translational medicine and collaboration with various stakeholders to advance medical knowledge and improve therapeutic outcomes. The institution emphasizes ethical conduct and rigorous scientific standards, ensuring that all research activities contribute meaningfully to the global healthcare landscape. Through its robust clinical trial infrastructure, UMC Utrecht plays a vital role in facilitating the development of new treatments and enhancing patient wellbeing.

Locations

Utrecht, , Netherlands

Groningen, , Netherlands

Nijmegen, , Netherlands

Amsterdam, , Netherlands

Patients applied

0 patients applied

Trial Officials

Nard Janssen, MD, DDS, PhD

Principal Investigator

UMC Utrecht

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Similar Trials