Comparing a Diagnostic and Treatment Strategy of Upfront CTCA With SOC in Patients With Chest Pain and Suspected CAD

Launched by ACADEMISCH MEDISCH CENTRUM - UNIVERSITEIT VAN AMSTERDAM (AMC-UVA) · Apr 19, 2022

Keywords

ClinConnect Summary

This clinical trial is studying a new approach to diagnosing and treating patients with chest pain who may have coronary artery disease (CAD). The researchers want to see if using a specific imaging test called computed tomography coronary angiography (CTCA) as the first step can help doctors better identify CAD and improve patient outcomes compared to the standard care, which can involve multiple tests and may not always be effective. The goal is to find out if this new strategy can reduce serious heart problems and also lower healthcare costs while improving patients' quality of life related to chest pain.

To participate in this trial, you need to be over 18 years old and have stable chest pain that could be a sign of CAD. However, if you recently had a heart attack or certain heart procedures, or if you have severe kidney problems, you may not be eligible. If you join the study, you will first undergo a CTCA test, and based on the results, your treatment will be tailored to your needs. The study aims to ensure that this new approach is as good as or better than the usual care in preventing serious heart issues.

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Eligibility criteria

• Inclusion Criteria:
• • \>18 years
• Exclusion Criteria:
• • Presentation with acute coronary syndrome
• • Acute coronary syndrome within last 3 months
• • History of obstructive coronary artery disease on imaging
• • History of PCI and/or CABG
• • Severe renal failure
• • Severe allergy to ionidated contrast medium
• • Known pregnancy
• • Patients with an estimated life expectancy of less than 1 year