Lactate Kinetics in Septic Shock

Launched by KAROLINSKA UNIVERSITY HOSPITAL · Apr 22, 2022

Keywords

ClinConnect Summary

This clinical trial is focused on understanding how lactate, a substance produced in the body during stress, behaves in patients with sepsis and septic shock. Researchers will give participants a special injection of labeled lactate to help track its movement and levels in the body. This study aims to improve our understanding of how sepsis affects lactate levels, which could help doctors better manage this serious condition.

To participate in this trial, individuals must be over 17 years old and diagnosed with sepsis, which is a severe infection that can lead to organ failure. They should also have a specific type of catheter placed in an artery for monitoring. However, people with certain conditions like mitochondrial defects, degenerative muscle diseases, or severe liver failure will not be eligible. Participants can expect to have their lactate levels monitored closely during the study, which will help researchers gather important information about sepsis. This trial is currently looking for volunteers to join and contribute to this important research.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Sepsis
• • Age \>17 years
• • Arterial catheter
• • Lactate \> 2 mmol at any time point prior to inclusion
• Exclusion Criteria:
• • Mitochondrial defect
• • Degenerative muscle disease
• • Terminal liver failure