Improving Pain Disability With the Use of Oral Cannabinoids

Launched by UNIVERSITY HEALTH NETWORK, TORONTO · Apr 22, 2022

Keywords

ClinConnect Summary

This clinical trial is exploring whether medical cannabis can help people manage chronic pain more effectively and safely. The study is a small pilot, which means it's a preliminary test to see how well the process works before a larger study is done. Over the course of three months, the researchers will look at how easy it is for participants to join and complete the study. This information will help them plan a more extensive trial in the future.

To participate, individuals need to be at least 25 years old, able to read and understand English, and must be experiencing ongoing pain that is not related to end-of-life care. However, those who have used certain cannabis products recently, have serious health conditions, or are pregnant or breastfeeding will not be eligible. Participants in the trial can expect to provide feedback on their experiences with medical cannabis and how it affects their pain levels. This is an important step in understanding how cannabis might be used as a treatment option for chronic pain.

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Eligibility criteria

• Inclusion Criteria:
• • 1. Age ≥ 25 years
• • 2. Able to understand and read English
• • 3. Experiencing chronic, non-palliative pain
• Exclusion Criteria:
• • 1. Use of nabilone, nabiximols or cannabis in the 30 days preceding study recruitment
• • 2. Known allergy to cannabis or any cannabinoid
• • 3. Serious ongoing medical issues (i.e., lung, liver, kidney or heart disease) that in the opinion of the Investigator would compromise the safety of the patient
• • 4. Current uncontrolled serious mental disorders such as schizophrenia, or psychosis
• • 5. Currently pregnant or breast-feeding (a negative urine pregnancy test must be obtained for women of child bearing potential during pretreatment evaluation)
• • 6. Men and women planning to start a family in the next 12 weeks
• • 7. Has declared a current alcohol or substance use disorder (excluding opioid use disorder)
• • 8. Currently using Methadone or Buprenorphine
• • 9. Patients who are naïve to pain treatments