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Search / Trial NCT05352893

Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Subjects With GPP

Launched by ANAPTYSBIO, INC. · Apr 25, 2022

Trial Information

Current as of July 06, 2025

Completed

Keywords

Il 36 Receptor Interleukin 36 Imsidolimab

ClinConnect Summary

This study will also characterize the pharmacokinetic (PK) profile of imsidolimab and explore the immunogenicity of imsidolimab in subjects with GPP.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • -Subject has a BSA affected with pustules (excluding palms and soles) ≥ 5%, a GPPPGA score ≥ 3 (moderate severity), and a PRS score ≥ 3 (moderate severity) at Day 1
  • Exclusion Criteria:
  • Subject has other form of psoriasis excluding psoriasis vulgaris
  • Subject flare is so severe that patient's life is at risk

About Anaptysbio, Inc.

Anaptysbio, Inc. is a clinical-stage biotechnology company focused on the discovery and development of innovative therapeutics for serious diseases. Leveraging its proprietary GigaMAB™ platform, Anaptysbio specializes in creating differentiated antibody products that target key immune pathways. The company's robust pipeline includes candidates aimed at addressing unmet medical needs across various therapeutic areas, including immunology and oncology. With a commitment to advancing science and improving patient outcomes, Anaptysbio is dedicated to translating groundbreaking research into effective treatments.

Locations

Largo, Florida, United States

Louisville, Kentucky, United States

Ann Arbor, Michigan, United States

Dallas, Texas, United States

Springville, Utah, United States

Melbourne, , Australia

Sydney, , Australia

Batumi, , Georgia

Tbilisi, , Georgia

Tbilisi, , Georgia

Tbilisi, , Georgia

Tbilisi, , Georgia

Bensheim, , Germany

Bonn, , Germany

Hanau, , Germany

Würzburg, , Germany

Pusan, , Korea, Republic Of

Seoul, , Korea, Republic Of

Seoul, , Korea, Republic Of

Seoul, , Korea, Republic Of

Cheras, , Malaysia

Johor Bahru, , Malaysia

Kota Bharu, , Malaysia

Kuala Lumpur, , Malaysia

Muar, , Malaysia

Putrajaya, , Malaysia

Casablanca, , Morocco

Casablanca, , Morocco

Oujda, , Morocco

Kraków, , Poland

Ossy, , Poland

Rzeszów, , Poland

Wrocław, , Poland

łódź, , Poland

Bucuresti, , Romania

Cluj Napoca, , Romania

Iaşi, , Romania

Svidník, , Slovakia

Barcelona, , Spain

Las Palmas De Gran Canaria, , Spain

Madrid, , Spain

Madrid, , Spain

Valencia, , Spain

Kaohsiung, , Taiwan

Taipei, , Taiwan

Taipei, , Taiwan

Taipei, , Taiwan

Bangkok, , Thailand

Chiang Mai, , Thailand

Khon Kaen, , Thailand

Pathum Thani, , Thailand

Sfax, , Tunisia

Sousse, , Tunisia

Tunis, , Tunisia

Ankara, , Turkey

Antalya, , Turkey

Istanbul, , Turkey

Istanbul, , Turkey

Istanbul, , Turkey

Nilufer, , Turkey

Patients applied

0 patients applied

Trial Officials

Bruce Randazzo, MD

Study Director

AnaptysBio, Inc.

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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