Contribution of Diaphragmatic Ultrasound for Monitoring Diaphragmatic Function in Patients With Amyotrophic Lateral Sclerosis

Launched by CENTRE HOSPITALIER UNIVERSITAIRE DIJON · Apr 25, 2022

Keywords

ClinConnect Summary

This clinical trial is studying a new way to monitor how well the diaphragm is working in patients with Amyotrophic Lateral Sclerosis (ALS), a serious disease that affects muscle control. The diaphragm is a crucial muscle for breathing, and problems with it can lead to serious respiratory issues. Currently, doctors use various tests to check diaphragm function, but these tests can be complicated and not always available. The trial aims to see if a simpler method called diaphragmatic ultrasound can effectively track diaphragm health and predict when patients might need breathing support.

To participate in this study, individuals must have a confirmed diagnosis of ALS and should not yet need non-invasive ventilation (a machine that helps with breathing). Participants should be adults who can understand and communicate in French. Those who have existing breathing issues that require ventilation or are in certain legal situations, such as being under guardianship, cannot join the trial. By taking part, patients will help researchers find a better way to monitor diaphragm function, which could lead to improved care for people with ALS.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patient with Amyotrophic Lateral Sclerosis
• • Certain or probable according to the revised Escorial criteria
• • no indication for non-invasive ventilation
• • Adult patient
• • Patient who has given oral consent
• • Patient who speaks and reads French
• Exclusion Criteria:
• • Patients with pre-existing diaphragmatic dysfunction requiring non-invasive ventilation
• • Person who is not affiliated to national health insurance
• • Person subject to a legal protection measure (curatorship, guardianship)
• • Patients deprived of their liberty
• • Pregnant, parturient or breastfeeding women