Prodromal Markers in Recurrent Dream Enactment Behaviors Without REM Sleep Without Atonia

Launched by CHINESE UNIVERSITY OF HONG KONG · Apr 25, 2022

Keywords

ClinConnect Summary

This clinical trial is studying a condition called REM Sleep Behavior Disorder (RBD), which involves unusual behaviors during dreaming, like acting out dreams while sleeping. The researchers are particularly interested in understanding a new idea called "prodromal RBD," where people show signs of RBD but do not fully meet the criteria for the disorder. This trial aims to investigate if certain behaviors, like acting out dreams without the usual sleep patterns, are linked to early signs of neurodegenerative diseases, such as Parkinson's disease.

To participate in this study, people need to be between 45 and 65 years old and have had repeated dream enactment behaviors. They will also need to have a specific score from a sleep behavior questionnaire indicating their symptoms. Participants will be interviewed and may have their sleep recorded to observe these behaviors. This trial is currently recruiting, and everyone is welcome to apply, regardless of gender. It's an important step in understanding sleep disorders and their potential links to other health issues.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age between 45 and 65 years old
• • RBDQ-HK behavior factor greater \> 8
• • Recurrent DEBs by interview and/or video analysis
• • Absence of sufficient RSWA
• Exclusion Criteria:
• • Age- and sex- matched with cases
• • RBDQ-HK behavior factor \< 8
• • No DEBs by either interview or video analysis
• • Absence of sufficient RSWA