Molecular Diagnosis of Systemic Autoinflammatory Diseases

Launched by INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE, FRANCE · May 3, 2022

Keywords

ClinConnect Summary

This clinical trial is focused on understanding systemic autoinflammatory diseases (SAIDs), which are rare conditions that cause inflammation in the body. Researchers aim to identify new genes and specific patterns in patients with these diseases, which can help in better diagnosing and treating them. The trial is currently recruiting participants of all ages, from children as young as 7 to adults, and it welcomes individuals of any gender.

To be eligible for this study, participants must have symptoms of inflammation that occur without an infection. This could include fever that comes and goes, stomach pain or diarrhea, joint or muscle aches, chest pain, skin problems, vision or hearing issues, or kidney problems. However, adults who have legal guardianship or protective measures in place are not eligible to participate. Those who join the trial can expect to undergo tests and assessments that will help researchers learn more about SAIDs and potentially improve care for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • A patient presenting with a clinical and biological aseptic inflammatory syndrome associating one or more of the following signs: spontaneously resolving fever, abdominal (pain, diarrhea), locomotor (arthralgia, myalgia), thoracic (pain, pericarditis), cutaneous, sensory (uveitis, deafness), or renal (amyloidosis) involvement.
• Exclusion Criteria:
• • Adult subject to legal protection measures (guardianship, curatorship, safeguard of justice).