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Search / Trial NCT05366933

B-Complex: A Nutraceutical SANS Countermeasure

Launched by NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (NASA) · May 5, 2022

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial, called B-Complex, is studying the effects of a daily supplement made from B vitamins on astronauts who may experience optic disc edema, a condition that can affect vision, during long space missions. The aim is to see if this supplement can help improve blood vessel function and maintain the health of the eye while in space. By doing this, researchers hope to understand better why some astronauts face vision changes after spending time in space and how this supplement might help.

To participate in this trial, you must be an astronaut selected for a 6 to 12-month mission on the International Space Station. It's important to note that if you are already taking B-vitamin supplements, you won't be eligible to join. If you take part, you can expect regular check-ups to assess your eye health and other important factors that could affect your vision. This research is crucial not just for the astronauts involved but also for understanding how to protect eye health during long-duration space flights.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • • Must be astronauts selected for 6-12 month missions on the International Space Station
  • Exclusion Criteria:
  • • Subjects taking B-vitamin supplements

About National Aeronautics And Space Administration (Nasa)

The National Aeronautics and Space Administration (NASA) is a leading U.S. government agency dedicated to the exploration of space and the advancement of aeronautics. With a mission to drive innovation and scientific discovery, NASA conducts groundbreaking research that extends to various fields, including human health and performance in space environments. By sponsoring clinical trials, NASA aims to understand the physiological and psychological effects of space travel on astronauts, ensuring their safety and well-being during long-duration missions. Through collaboration with scientific communities and institutions, NASA harnesses cutting-edge technology and expertise to address complex health challenges inherent in space exploration, ultimately contributing to both space science and terrestrial health advancements.

Locations

Houston, Texas, United States

Patients applied

TN

1 patients applied

Trial Officials

Sara R Zwart, PhD

Principal Investigator

UTMB

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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