The Effects of Chiropractic Care in Adults With Subclinical Spinal Pain
Launched by RIPHAH INTERNATIONAL UNIVERSITY · May 5, 2022
Trial Information
Current as of October 25, 2025
Completed
Keywords
ClinConnect Summary
There is growing evidence that chiropractic care positively impacts various aspects of central and autonomic nervous system function. A single session of chiropractic adjustment has shown to alter pre-frontal cortex (PFC) activity, but there is a lack of robust research investigating the long-term benefits of such PFC changes. This study aims to investigate long term and retention (in a subgroup) effects of Chiropractic care (CC) on neurological, behavioral, immunological functions and health-related quality of life in adults with subclinical pain. In these parallel-group randomized control...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • aged between 18 and 60 years
- • have subclinical spinal pain
- Exclusion Criteria:
- • no evidence of spinal dysfunction is present, they are in current pain (above 3/10 on VAS)
- • have sought previous treatment for their spinal issues
- • are unable to perform the assessment procedures due to contraindications or movement limitations
- • diagnosed immune dysfunction
- • utilizing a prescribed immunosuppressive medication
- • they have uncontrolled asthma
- • have nasal polyps
- • use of an intranasal steroid spray one month or less before the study
- • are HIV-positive
- • unable or unwilling to comply with the study protocol
- • a history of drug abuse
- • are participating in another research study during the time of data collection.
- • have any diagnosed comorbidity or concomitant disease
- • donated blood within last month
- • have allergies to yeast or yeast-derived products
- • have chronic sinusitis and/ or recent (within the last six weeks) episodes of acute sinusitis.
About Riphah International University
Riphah International University is a leading educational institution based in Pakistan, dedicated to advancing healthcare and medical research through innovative clinical trials. With a commitment to excellence in research and education, Riphah emphasizes ethical standards and scientific integrity in its clinical studies. The university collaborates with various stakeholders, including healthcare professionals and industry partners, to enhance patient outcomes and contribute to the global body of medical knowledge. Through its robust research programs, Riphah International University aims to foster a culture of inquiry and improve healthcare delivery both locally and internationally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Rawalpindi, Pakistan
Patients applied
Trial Officials
IMRAN KHAN NIAZI, PhD
Principal Investigator
New Zealand College of Chiropractic
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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