Mobility and Voiding Exercises in Older Women with Urinary Incontinence (MoVEonUp)

Launched by UNIVERSITY OF PENNSYLVANIA · May 10, 2022

Keywords

ClinConnect Summary

The MoVEonUp trial is studying how specific exercises and training can help older women who experience a strong and sudden urge to urinate, known as urinary urge incontinence, while also reducing their risk of falling. In this study, women aged 70 and older who live independently and are not very physically active can participate. They will be randomly assigned to either a group that receives balance and strength training, bladder training, and home safety assessments, or a control group that will receive informative booklets on fall prevention and tips for managing urinary incontinence.

If you qualify for the trial, you can expect to engage in exercises designed to improve your strength and balance, as well as techniques to manage your urinary urges. Participants will also have their home environments assessed to reduce fall risks. It’s important to know that you need to be able to participate in an exercise program safely, and there are certain health conditions that might prevent you from joining. Overall, this study aims to improve both urinary control and safety for older women living in the community.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Female
• • 70 or older
• • Living independently in the community
• • Willingness to be randomized.
• • Ability to read and understand English
• • Be able to provide informed consent
• • Low physical activity (physically active for 30 minutes or more less than or equal to 2 days per week on average over the past 6 months) per PAS
• • Ambulatory (defined as patient not confined to bed or wheelchair OR ability to walk with or without an assistive device)
• • Self-reported moderate to severe urge-predominant UI based on the ICIQ-SF \> 6 (Q 1+2+3)
• • Not planning to initiate new UI or overactive bladder (OAB) treatment during the study duration
• • Capable of participation in an exercise program without exacerbating any pre-existing condition(s), as determined by the study PI or designee
• Exclusion Criteria:
• • Pelvic organ prolapse passed the hymen (per patient report)
• • Undergoing active treatment for cancer (other than non-melanoma skin cancer)
• • Uncorrected visual or hearing loss.
• • Other urinary conditions or procedures that may affect continence status for example: urethral diverticulum, previous augmentation cystoplasty
• • Progressive neurodegenerative disease e.g. Parkinson's disease, multiple sclerosis per patient report
• • History of stroke or carotid sensitivity (i.e. syncopal falls) per patient report
• • Unstable cardiac disease per patient report
• • Fracture or joint replacement within the last six months per patient report
• • Significant cognitive impairment (defined as a modified TICs score of \< 27)
• • Per PI discretion, participant cannot enroll in study