Microbial Colonization of Oral Probiotics

Launched by BLIS TECHNOLOGIES LIMITED · May 11, 2022

Keywords

ClinConnect Summary

This is a double-blind, randomized controlled colonization pilot study with no cross over to evaluate the colonization efficacy of lozenges and powders containing two different commercially available probiotic bacteria (S. salivarius K12 ) or S. salivarius M18 with or without 2 different prebiotic sugars or their combinations.

Participants will be randomly assigned to one of the 12 groups consuming probiotic lozenge or powder containing Streptococcus salivarius K12 or S. salivarius M18 with or without prebiotics (e.g. sugars that may promote probiotic activity) over a seven day period. Sal...

Gender

ALL

Eligibility criteria

• Inclusion criteria:
• • 1. Male or Female 18y - 80y age
• • 2. In general good health 18 - 80 years of age.
• • 3. Practice good oral hygiene.
• Exclusion criteria:
• • 1. Have a history of autoimmune disease or are immunocompromised.
• • 2. Are on concurrent antibiotic therapy or regular antibiotic use within last 1 week
• • 3. History of allergy (e.g. dairy).