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Search / Trial NCT05376891

Met Non Small Cell Cancer Registry (MOMENT)

Launched by EMD SERONO RESEARCH & DEVELOPMENT INSTITUTE, INC. · May 11, 2022

Trial Information

Current as of August 19, 2025

Recruiting

Keywords

Disease Registry Me Tex14 Skipping Alterations

ClinConnect Summary

The MOMENT clinical trial is a global study designed to gather important information about people with advanced non-small cell lung cancer (NSCLC) who have a specific genetic change known as METex14. This trial aims to understand how different treatments are working and to see how patients respond to their therapies over time. By collecting detailed information about participants' health, treatment choices, and outcomes, researchers hope to improve our understanding of this type of cancer and its treatments.

To be part of this study, participants need to be adults with advanced NSCLC (stages IIIB-IV) and have confirmed METex14 genetic changes. They should also be starting or currently receiving treatment for their cancer. However, those already taking part in another clinical trial cannot join this registry. Participants will regularly provide information about their health and treatment, helping to create a clearer picture of how to best manage this challenging condition. This is an exciting opportunity to contribute to cancer research and potentially improve future treatments for others.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Participants who signed ICF
  • Participants with advanced stage (stages IIIB-IV) NSCLC (all histologies) and Confirmed METex14 skipping alterations (by valid assay)
  • Participants who are starting or are already being treated with systemic therapy
  • Exclusion Criteria:
  • Participants who are enrolled in a clinical trial

About Emd Serono Research & Development Institute, Inc.

EMD Serono Research & Development Institute, Inc. is a leading biopharmaceutical company dedicated to advancing innovative therapies for patients with serious medical conditions. As a subsidiary of Merck KGaA, Darmstadt, Germany, EMD Serono focuses on areas such as oncology, neurology, and endocrinology, leveraging cutting-edge research and development to address unmet medical needs. Committed to scientific excellence and patient-centric solutions, the institute fosters collaboration with healthcare professionals and research organizations to drive clinical trials and bring transformative treatments to market.

Locations

Milano, , Italy

Leiden, , Netherlands

Nashville, Tennessee, United States

Amsterdam, , Netherlands

Haifa, , Israel

Paris, , France

Lille, , France

Darmstadt, , Germany

Haifa, , Israel

Jerusalem, , Israel

Tel Aviv, , Israel

Afula, , Israel

Ramat Gan, , Israel

Birmingham, , United Kingdom

Bournemouth, , United Kingdom

Milano, , Italy

Sint Niklaas, , Belgium

London, , United Kingdom

Sevilla, , Spain

Madrid, , Spain

Harrow, , United Kingdom

Tampere, , Finland

Olomouc, , Czechia

Groningen, , Netherlands

Varese, , Italy

Turku, , Finland

Porto, , Portugal

Guildford, , United Kingdom

Birmingham, , United Kingdom

Toulouse, , France

Lisboa, , Portugal

Roeselare, , Belgium

Cholet, , France

Leiden, South Holland, Netherlands

Toronto, , Canada

Chemnitz, , Germany

Columbus, Ohio, United States

Ottawa, , Canada

Valencia, , Spain

Lorient, , France

Chelsea, , United Kingdom

Roma, , Italy

Linköping, , Sweden

Sutton Coldfield, , United Kingdom

Las Palmas De Gran Canaria, , Spain

Heidelberg, , Germany

Ramat Gan, , Israel

Wien, , Austria

Rockland, Massachusetts, United States

Fort Lauderdale, Florida, United States

Klagenfurt Am Wörthersee, , Austria

Yvoir, , Belgium

Toronto, , Canada

Grosshansdorf, , Germany

Ashdod, , Israel

Ashdod, , Israel

Haifa, , Israel

Haifa, , Israel

Haifa, , Israel

Haifa, , Israel

Jerusalem, , Israel

Ramat Gan, , Israel

Tel Aviv Yafo, , Israel

Tel Aviv, , Israel

Orbassano (To), , Italy

Orbassano, , Italy

Lisboa, , Portugal

Porto Covo, , Portugal

Malaga, , Spain

Bedford, , United Kingdom

Ottawa, , Canada

Praha 8, , Czechia

Lille Cedex, , France

Lyon Cedex 08, , France

Paris Cedex 05, , France

Paris, , France

Toulouse, , France

Grosshansdorf, , Germany

Löwenstein, , Germany

Haifa, , Israel

Petach Tikva, , Israel

Napoli, , Italy

Rome, , Italy

Torino, , Italy

Groningen, , Netherlands

Porto, , Portugal

Barcelona, , Spain

Barcelona, , Spain

Madrid, , Spain

Sevilla, , Spain

Liverpool, , United Kingdom

Preston, , United Kingdom

Patients applied

0 patients applied

Trial Officials

Medical Responsible

Study Director

Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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