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Search / Trial NCT05378022

Effects of Nasal-spraying LiveSpo Navax in Treatment of Influenza Virus in Children

Launched by NATIONAL CHILDREN'S HOSPITAL, VIETNAM · May 12, 2022

Trial Information

Current as of June 08, 2025

Completed

Keywords

Influenza Virus (Flu) Acute Respiratory Tract Infections (Art Is) Children Nasal Spraying Probiotics Viral Load Co Infection Bacteria Cytokines Bacillus Spores

ClinConnect Summary

Influenza virus types A and B is the common virus that causes Acute Respiratory Tract Infections (ARTIs) with a high risk of bronchiolitis for young children and infants. Influenza-infection symptoms range from mild fever, cough, runny nose, and wheezing to severe symptoms such as fast pulse, fast breathing, and respiratory failure. In a systematic review and meta-analysis of the global burden of seasonal influenza respiratory infections in young children, they estimated that 28.000 - 111.500 children under the age of 5 die as a result of influenza infections in 2008, of which 99% of these ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Children (male/female) aged from 4 months to 7 years
  • Admitted to hospital due to upper respiratory infection
  • Influenza A and B positive by rapid test
  • Parents of the pediatric patient agree to participate in the study, explain and sign the research consent form.
  • Exclusion Criteria:
  • Newborn babies
  • Having a history of drug allergies
  • Need oxygen therapy
  • Discharged before day 2
  • Lost to follow-up
  • Withdrawn from the trial
  • Continuing in the trial but missing data
  • Meeting the criteria for psychiatric disorders other than depression and/or anxiety.

About National Children's Hospital, Vietnam

National Children's Hospital, Vietnam, is a leading pediatric healthcare institution committed to advancing child health through innovative research and clinical trials. With a focus on improving treatment outcomes and enhancing healthcare delivery for children, the hospital collaborates with international and local partners to conduct rigorous clinical studies across various pediatric specialties. Its multidisciplinary team of healthcare professionals and researchers is dedicated to fostering a safe and ethical environment for clinical research, ensuring the highest standards of care and scientific integrity in all trials. Through its initiatives, National Children's Hospital aims to contribute significantly to the global body of pediatric knowledge and improve health outcomes for children in Vietnam and beyond.

Locations

Hanoi, , Vietnam

Patients applied

0 patients applied

Trial Officials

Tu T Tran, PhD. MD.

Principal Investigator

International Center, Vietnam National Children's Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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