The Effect of Hyperoxia on Ventilation During Recovery From General Anesthesia

Launched by STANFORD UNIVERSITY · May 12, 2022

Keywords

ClinConnect Summary

This clinical trial is studying how extra oxygen helps people breathe better after they wake up from general anesthesia. Researchers want to see if providing more oxygen for 90 minutes right after the breathing tube is removed can improve recovery and reduce the risk of breathing problems after surgeries like kidney or prostate removal using robotic techniques.

To participate in the trial, patients should be between 18 and 80 years old and generally healthy, with a body mass index (BMI) of less than 40. They should not have serious lung issues, major neurological or heart problems, or be on strong pain medications like opioids. If eligible, participants will receive oxygen or regular air after their surgery and will be monitored to see how well they breathe during the recovery period. This study aims to find out if extra oxygen can make a difference in recovery after surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • American Society of Anesthesiologists (ASA) physical status I-III
• • Body mass index (BMI) less than 40 kg/m2
• • Scheduled to undergo robotic-assisted radical laparoscopic nephrectomy or prostatectomy.
• Exclusion Criteria:
• • Patients with a diagnosis of chronic obstructive pulmonary disorder (COPD), severe neurological, cardiopulmonary, psychiatric, or untreated thyroid disorder
• • Chronic pain condition that is being treated with opioids
• • Patients with a hematocrit lower than 30% at the end of surgery, or those with an excessive blood loss, requiring transfusion of blood products during surgery.