Personalized Perioperative Analgesia Platform (PPAP) for Cesarean Section

Launched by SENTHIL SADHASIVAM · May 12, 2022

Keywords

ClinConnect Summary

This clinical trial is investigating a new approach to managing pain for women who are having a cesarean section (C-section). The goal is to create a personalized pain relief system that can help reduce the use of opioids, which are strong pain medications, and minimize potential problems for both mothers and their babies, especially for breastfeeding mothers. By using this new method, researchers hope to improve recovery experiences and reduce any serious side effects related to opioid use.

To be eligible for this trial, participants must be adult women over 18 years old who are scheduled for an elective C-section and are open to receiving opioid pain relief while in the hospital. However, women with certain health conditions, a history of opioid misuse, or severe pain before the surgery cannot participate. If you join the trial, you can expect to receive personalized pain management support during and after your surgery. This study is currently looking for participants, and your involvement could help lead to better pain management strategies for future mothers.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Adult women (\>18 yr) All races American Society of Anesthesiologists Classification (ASA) physical status: 1 to 3 undergoing elective Cesarean section that are willing to receive in-patient opioids.
• Exclusion Criteria:
• • 1. Health conditions including uncontrolled diabetes (gestational or pre-existing) or hypertension (pre-eclampsia, eclampsia, or chronic)
• • 2. Any history of opioid misuse before or during pregnancy-per self-report and clinical notes
• • 3. Preoperative severe pain and opioid use/misuse, allergy to oxycodone
• • 4. Allergy to oxycodone
• • 5. Significant neurological disorders, liver and renal diseases