Response to Influenza Vaccination in Pediatric Oncology Patients

Launched by ST. JUDE CHILDREN'S RESEARCH HOSPITAL · May 17, 2022

Keywords

ClinConnect Summary

This clinical trial is studying how well the flu vaccine works in children and teenagers who are being treated for blood-related cancers, such as leukemia. The researchers want to understand if these patients can build a good immune response to the vaccine, especially since they are at a higher risk for serious complications if they get the flu. The study aims to see how effective the vaccine is over time and to monitor any signs of the flu in the participants.

To be eligible for this trial, patients must be 18 years old or younger and should be receiving treatment at St. Jude Children's Research Hospital for a blood cancer. They also need to be able to receive the current seasonal flu vaccine. Participants who join the study will get vaccinated and then have their immune response checked at various times after vaccination to see how well their bodies are responding. This study is important as it could help improve flu prevention strategies for young patients undergoing cancer treatment.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patient ≤ 18 years old at the time of consent receiving care at St. Jude Children's Research Hospital
• • Diagnosed with a hematological malignancy
• • Eligible to receive the current seasonal influenza vaccine
• Exclusion Criteria:
• • • Previously received at least one dose of the current seasonal influenza vaccine.