Effect of FMD on Colorectal Cancer Patients

Launched by FUDAN UNIVERSITY · May 19, 2022

Keywords

ClinConnect Summary

This clinical trial is investigating the effects of a special diet called the Fasting Mimicking Diet (FMD) on patients recovering from surgery for colorectal cancer. Previous research suggests that this diet may help protect healthy cells while making cancer cells more vulnerable to treatments like chemotherapy. The trial aims to see how well the FMD works for patients who have just undergone surgery for colorectal cancer, focusing on their recovery and overall outcomes.

To participate in this study, you need to be between 18 and 80 years old and undergoing your first surgery for colorectal cancer. You should be in good health with specific criteria regarding your weight and organ functions. If you join the trial, you will follow a carefully designed diet after your surgery and will be regularly monitored to evaluate how the diet impacts your recovery. It's important to note that certain health conditions may prevent you from participating, so discussing your eligibility with your doctor is essential.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age 18 \~ 80 years old
• • 2. Patients undergoing radical colorectal cancer resection for the first time
• • 3. Preoperative clinical tumor stage III
• • 4. ASA grade I-III grade
• • 5. With BMI 19-32 kg/m2
• • 6. Adequate liver function, adequate renal function and normal cardiac function
• • 7. Willing to participate in the research of the subject and agree to follow up regularly
• Exclusion Criteria:
• • 1. Evidence of distant metastasis before surgery
• • 2. Before surgery, have received treatment of neoadjuvant chemotherapy
• • 3. Type 1 diabetes or intensive insulin therapy
• • 4. Allergies for FMD content
• • 5. Combined with severe primary diseases such as severe immune system or autoimmune system or long-term using of glucocorticoids or immunosuppressant
• • 6. History of opioid abuse, mental illness or cognitive impairment