Sodium Lowering Vascular Effects Trial

Launched by TULANE UNIVERSITY · May 19, 2022

Keywords

ClinConnect Summary

The Sodium Lowering Vascular Effects Trial is studying how reducing dietary sodium (salt) can affect heart and blood vessel health, particularly in people with high blood pressure. The goal is to understand how lowering sodium might help prevent heart-related problems, especially for those already at risk. The trial is currently looking for participants who are 40 years or older and have elevated blood pressure, whether or not they are taking medication for it.

If you decide to join, you’ll be part of a study that explores the effects of dietary changes on your cardiovascular health. However, there are some criteria to keep in mind. For example, you should not have severe kidney problems, a history of heart disease, or be pregnant or breastfeeding. Participants will receive guidance on dietary changes and will be monitored throughout the trial. This study aims to provide valuable insights that could lead to better heart health recommendations in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Men or women aged ≥40 years. Individuals \<40 years are at a low risk for clinical and subclinical CVD
• • Elevated BP or hypertension (systolic BP ≥120 mmHg and diastolic BP ≥80 mmHg with or without use of antihypertensive medications)
• Exclusion Criteria:
• • Glomerular filtration rate (eGFR) \<30 or end-stage renal disease (kidney transplant or chronic dialysis)
• • History of cardiovascular disease
• • Shift worker or regularly work at night
• • Cancer requiring chemotherapy or radiation treatment in the previous two years
• • Current pregnancy or breastfeeding or plans to become pregnant during the study
• • Consumption of ≥21 alcoholic drinks/week
• • Current participation in another lifestyle intervention or drug trial
• • Current residence or planned residence that makes it difficult to meet trial requirements
• • Other concerns regarding ability to meet trial requirements (at the discretion of the study coordinator)