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Search / Trial NCT05389930

Cannabis' Impact on Alcohol Consumption

Launched by BROWN UNIVERSITY · May 20, 2022

Trial Information

Current as of August 22, 2025

Recruiting

Keywords

Alcohol Cannabis Marijuana Addiction Cannabinoid Tetrahydrocannabinol Cannabidiol

ClinConnect Summary

This clinical trial is studying how different types of cannabis—specifically, one high in THC (the part of cannabis that can make you feel high) and another high in CBD (which doesn’t produce a high)—affect alcohol consumption in people who drink heavily. Participants will take cannabis while also receiving either alcohol or a placebo (a substance with no active ingredients). The researchers want to see if cannabis influences how much alcohol people choose to drink.

To be eligible for this study, participants need to be between 21 and 50 years old, speak English, and have used cannabis and consumed a lot of alcohol in the past two months. It's important for them to be in good health and weigh under 250 pounds. Throughout the trial, participants will be monitored to ensure they are not pregnant and do not have other drugs in their system. Those who are interested in quitting drinking or using cannabis will not be eligible. If chosen, participants can expect to take part in several visits where they will receive either cannabis or a placebo and answer questions about their drinking choices. This study is currently recruiting and aims to enroll up to 350 people.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Age 21 to 50
  • English-speaking
  • cannabis smoking in past two months
  • heavy drinking in past two months
  • in good physical health and weighing \< 250 lbs
  • zero breath alcohol at each visit
  • Exclusion Criteria:
  • positive pregnancy test
  • nursing
  • positive urine toxicology screen for drugs other than cannabis
  • interest to quit or receive treatment for cannabis or alcohol use

About Brown University

Brown University, a prestigious Ivy League institution located in Providence, Rhode Island, is committed to advancing medical research and improving public health through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, Brown leverages its world-class faculty and state-of-the-art facilities to conduct rigorous studies across various fields, including medicine, public health, and biomedical sciences. The university's dedication to ethical research practices and participant safety ensures that all clinical trials are designed to yield meaningful insights that contribute to the development of new therapies and health interventions.

Locations

Providence, Rhode Island, United States

Patients applied

0 patients applied

Trial Officials

Jane Metrik, PhD

Principal Investigator

Brown University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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