Global BurdEn of MechanIcal VeNtilatIon (GEMINI). VeNtilatIon (GEMINI Study) 2022 for VENTILAGROUP.

Launched by HOSPITAL UNIVERSITARIO GETAFE · May 22, 2022

Keywords

ClinConnect Summary

The GEMINI study is looking at how different methods of mechanical ventilation affect critically ill patients around the world, especially after the changes brought on by the COVID-19 pandemic. Mechanical ventilation is a medical treatment that helps patients breathe when they can't do so on their own. This study aims to understand how various ventilation strategies impact patient outcomes, which could help doctors provide more personalized care in the future.

To be eligible for this study, participants need to be adults aged 18 or older who are in the Intensive Care Unit (ICU) and require mechanical ventilation for more than 12 hours due to serious breathing problems. This includes patients using invasive methods, like a breathing tube, or non-invasive methods, like special masks that help them breathe better. Participants will be monitored to see how they respond to treatment over the next six months. By analyzing the data collected, researchers hope to uncover patterns that could lead to better care for patients on mechanical ventilation.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • All consecutive adult patients (≥ 18 years old) who are admitted to the ICU and require invasive mechanical ventilation (endotracheal tube or tracheostomy) longer than 12 hours. 2. Adult patients admitted to the ICU and require advanced respiratory support (high flow oxygen nasal cannula \[HFONC\], or noninvasive ventilation \[NIV\] BIPAP or CPAP with oronasal, nasal, helmet or facial mask) with acute respiratory failure defined as PaO2/ fraction of inspired oxygen (FiO2), \[PaO2/FiO2\] ratio \<300, or the pulse oximetric saturation (SpO2/FiO2 ) ratio \< 315 for more than 1 hour. 3. Adult patients in whom mechanical ventilation were started outside the study ICU at the same Institution and/or a different Institution, including Emergency Room, Operating Room (OR), /or were then transferred to the ICU at the participating center
• Exclusion Criteria:
• * The following ICUs will be excluded:
• • 1. Pediatric ICU.
• • 2. Post-Operators Anesthesia Recovery Room. 2. Patients less than 18 years old. 3. Patients admitted after elective surgery and who require mechanical ventilation for less than 12 hours (excepting patients who receive non-invasive ventilation). 4. Patients will be excluded if they were transferred to participating ICUs without a documented intubation time, or underwent a tracheotomy at prior to ICU admission. 5. Patients that were at participating ICUs for 24 hours or more, were readmitted during the study period