Effect of Phlebotomy on Heartrate in Polycythemia Patients

Launched by LEIDEN UNIVERSITY MEDICAL CENTER · May 25, 2022

Keywords

ClinConnect Summary

This clinical trial is studying how regular blood donation, known as phlebotomy, affects the heart rate of patients with a condition called polycythemia, where the body makes too many red blood cells. The researchers will monitor participants' heart rates using wearable devices for a week before and a week after each of three scheduled blood donations. The goal is to understand if and how phlebotomy influences heart rate over time.

To participate, individuals must be at least 18 years old, have polycythemia requiring phlebotomy at least every four months, and own a smartphone. Participants should be in generally good health, as those with serious heart issues, certain other medical conditions, or upcoming surgeries will not be included. If eligible, you can expect to wear a device that tracks your heart rate and attend regular phlebotomy appointments during the study. This research could help improve care for patients with polycythemia by providing valuable insights into how blood donation impacts heart health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with polycythaemia, requiring phlebotomy on a regular basis (at least every 4 months)
• • Subjects aged ≥18 years
• • In possession of a smartphone
• • Life expectancy ≥ 3 months
• Exclusion Criteria:
• • Poor performance/functional status (Eastern Cooperative Oncology Group system ECOG ≥3)
• • Participants with known arrhythmias or other significant cardiological conductivity disorders (Paroxysmal atrial fibrillation is allowed)
• • Hospitalized subjects
• • Subjects with a pacemaker.
• • Subjects with a secondary polyglobulia due to eg smoking or other pulmonary issues.
• • Scheduled oncological treatments or surgery during the study period.