Research on Optimal Diagnosis and Treatment of Cardiorenal Syndrome

Launched by NANJING FIRST HOSPITAL, NANJING MEDICAL UNIVERSITY · May 26, 2022

Keywords

ClinConnect Summary

This clinical trial is studying a condition called cardiorenal syndrome, which involves problems in both the heart and kidneys. Researchers aim to understand the different types of this syndrome, their causes, and the best ways to treat them. The trial will look at patients with various stages of heart and kidney diseases, including conditions like heart failure and kidney injury. By gathering information about these conditions, the study hopes to find more effective treatment options.

To participate in the trial, individuals must be between the ages of 65 and 74 and have a specific type of cardiorenal syndrome, as defined by expert guidelines. This includes conditions where heart problems lead to kidney issues or vice versa. Unfortunately, pregnant or breastfeeding women and those who cannot follow medication plans are not eligible to join. Participants can expect to help researchers learn more about these diseases, which could lead to better care for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients meet the diagnosis of various types of cardiorenal syndrome according to the classification standards of various types formulated by KDIGO and ADQI expert consensus. Different syndromes were identified and classified into five subtypes. Acute CRS (type 1): acute worsening of heart function (AHF-ACS) leading to kidney injury and/or dysfunction. Chronic cardio-renal syndrome (type 2): chronic abnormalities in heart function (CHF-CHD) leading to kidney injury and/or dysfunction. Acute reno-cardiac syndrome (type 3): acute worsening of kidney function (AKI) leading to heart injury and/or dysfunction. Chronic reno-cardiac syndrome (type 4): chronic kidney disease leading to heart injury, disease, and/or dysfunction. Secondary CRS (type 5): systemic conditions leading to simultaneous injury and/or dysfunction of heart and kidney.
• Exclusion Criteria:
• • Pregnant or breastfeeding women; Female patients with recent birth plans; Patients who cannot follow up on medications.