Prandial Metabolic Phenotype in Adults

Launched by TEXAS A&M UNIVERSITY · May 27, 2022

Keywords

ClinConnect Summary

This clinical trial, titled "Prandial Metabolic Phenotype in Adults," is exploring how aging affects our bodies' protein metabolism, which includes how our bodies build up and break down proteins. Researchers believe that understanding these changes can help identify ways to improve health and function in older adults. They will use a special method to study metabolism in a large group of people aged 60 to 80, focusing on how amino acids, the building blocks of proteins, relate to age-related health issues.

To participate in this study, individuals must be between 60 and 80 years old, have maintained a stable body weight for the last three months, and be in good health. Participants should be able to walk and move around independently or with assistance and be comfortable lying down for several hours during the study. Those with certain medical conditions or recent illnesses, as well as pregnant individuals, will not be eligible. If you join the study, you'll help researchers learn more about how aging affects metabolism, which could lead to better health solutions for older adults.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age: 60-80, inclusive
• • Stable body-weight (± 5%) for the past 3 months
• • Subject is judged to be in satisfactory health based on medical history, physical examination, and laboratory screening evaluations.
• • Ability to walk, sit down and stand up independently or with walking mobility aids
• • Ability to lie in supine or elevated position for up to 7 hours
• • Willingness and ability to comply with the protocol
• Exclusion Criteria:
• • Established diagnosis of current malignancy
• • History of untreated metabolic diseases including hepatic or renal disorder
• • Presence of acute illness or metabolically unstable chronic illness
• • Presence of fever within the last 3 days
• • Use of short course of oral corticosteroids within 4 weeks preceding study day
• • (Possible) pregnancy
• • Failure to give informed consent or Investigator's uncertainty about the willingness or ability of the subject to comply with the protocol requirements
• • Already enrolled in another clinical trial and that clinical trial interferes with participating in this study
• • Any other condition according to the PI or nurse that was found during the screening visit, that would interfere with the study or safety of the patient