Transradial Versus Transfemoral Access for Cerebral Angiography
Launched by HUASHAN HOSPITAL · Jun 1, 2022
Trial Information
Current as of July 09, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is comparing two different ways to access blood vessels for a procedure called cerebral angiography, which helps doctors examine the blood vessels in the brain. The two methods being studied are Transradial access (TRA), which involves using an artery in the wrist, and Transfemoral access (TFA), which uses an artery in the groin. Researchers want to find out which method is easier, safer, and more successful for patients needing this diagnostic test.
To participate in this study, you need to be between 18 and 80 years old and scheduled for a cerebral angiography. You should have a suitable wrist artery for the TRA method and a good score on a scale that measures how well you can perform daily activities. However, some people may not be eligible, such as those with certain vascular diseases or other specific health issues. If you join the trial, you can expect to undergo the procedure using one of the two access methods, and you’ll be closely monitored to ensure your safety throughout the study.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Age between 18 and 80 years old;
- • 2. Scheduled to undergo diagnostic cerebral angiography;
- • 3. Suitable for cerebral angiography via TRA and TFA access, with a radial artery diameter ≥2mm confirmed by ultrasonography;
- • 4. Modified Rankin Scale (mRS) score ≤2;
- • 5. Provided written informed consent.
- Exclusion Criteria:
- • 1. Severe stenosis of the radial, brachial, subclavian, brachiocephalic, iliac or common femoral arteries, or any significant vascular disease (such as aortic aneurysm, etc.) that may obstruct guidewire passage;
- • 2. Arteriovenous fistula for hemodialysis present in the right upper limb;
- • 3. Planned interventional surgery within 24 hours of the initial study angiography;
- • 4. Requirement for cerebral angiography in an emergency department;
- • 5. Use of general anesthesia;
- • 6. Any contraindication to cerebral angiography, such as allergy or intolerance to the contrast media, uncorrected severe coagulation disorders, arterial dissection in the target vessel, puncture site infection, or renal insufficiency (Creatinine \[Gr\] \> 3 times of the upper limit of normal \[ULN\]), etc.;
- • 7. Women who are pregnant or planning to become pregnant within 1 year;
- • 8. Participation in another clinical trial;
- • 9. Any other condition deemed unsuitable for participation by the investigator.
About Huashan Hospital
Huashan Hospital, affiliated with Fudan University in Shanghai, is a leading medical institution renowned for its commitment to innovative research and high-quality patient care. As a prominent clinical trial sponsor, Huashan Hospital leverages its extensive expertise in various medical disciplines to advance the development of new therapies and treatment modalities. The hospital's state-of-the-art facilities and multidisciplinary teams facilitate rigorous clinical investigations, ensuring adherence to ethical standards and regulatory compliance. With a focus on improving patient outcomes, Huashan Hospital actively collaborates with academic and industry partners to drive forward-thinking research initiatives that address critical healthcare challenges.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Shanghai, Shangai, China
Patients applied
Trial Officials
Yuxiang Gu, PhD,MD
Study Chair
department of Neurosurgery, Huashan Hospital,Fudan University
Wei Ni, PhD,MD
Study Director
department of Neurosurgery, Huashan Hospital,Fudan University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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