Comparison of Three Different Antibiotic Treatments Against Recurrent Urinary Tract Infections in Catheterized Patients
Launched by UNIVERSITY OF SOUTHERN DENMARK · May 30, 2022
Trial Information
Current as of July 09, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at how effective three different treatments are for patients who have recurring urinary tract infections (UTIs) while using a long-term urinary catheter. The study aims to compare a single antibiotic treatment, a combination of antibiotics, and a method called bladder lavage (washing out the bladder) to see which one works best. This is important because many patients with catheters face challenges due to infections caused by bacteria that are resistant to standard treatments.
To participate in this trial, patients need to have a long-term urinary catheter and experience frequent UTIs, leading to symptoms like pain, fever, or changes in urine. The trial will not include patients with certain types of urinary catheters or other specific conditions. Those who join the study can expect to be randomly assigned to one of the three treatment groups, and researchers will monitor their progress to determine which treatment is most effective. This research could help improve care for patients dealing with these tough infections in the future.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients, who have long-term urinary catheter in situ with recurrent UTI and are admitted or referred to an ambulatory due to acute episode of UTI (acute local symptoms include pyuria or urine stick positive, suprapubic pain or tenderness, costovertebral angle pain or tenderness, catheter obstruction, or acute hematuria) or urosepsis (If a bacteriuric patient has positive blood culture with fever, leukocytosis and high C-reaction protein, and the cultured bacteria in urine and blood are consistent, urosepsis is diagnosed) will be included to the project.
- Exclusion Criteria:
- • Patients with nephrostomy catheters, J-J catheter, bricker bladder or urinary stones will be excluded from the project.
About University Of Southern Denmark
The University of Southern Denmark (SDU) is a prominent research institution dedicated to advancing knowledge and innovation across various fields, including health sciences. As a clinical trial sponsor, SDU is committed to conducting rigorous and ethically sound research aimed at improving patient outcomes and informing clinical practices. Leveraging its multidisciplinary expertise and state-of-the-art facilities, SDU collaborates with healthcare professionals, industry partners, and regulatory bodies to develop and execute clinical trials that adhere to the highest standards of scientific integrity and compliance. Through its research initiatives, SDU seeks to contribute to the global body of medical knowledge and enhance the quality of healthcare delivery.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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