Comparison of the Analgesic Effect of 2 Shoulder Infiltrations

Launched by CENTRE HOSPITALIER DE L'UNIVERSITÉ DE MONTRÉAL (CHUM) · Jun 3, 2022

Keywords

ClinConnect Summary

This clinical trial is studying the effectiveness of two different types of injections to relieve shoulder pain caused by osteoarthritis, which is a painful condition affecting the joints. The injections being compared are Cingal (which contains a mixture of sodium hyaluronate and cortisone) and a standard cortisone injection. Researchers hope to find that the Cingal injection provides better pain relief than the cortisone alone for people with moderate to severe shoulder osteoarthritis.

To participate in this study, individuals must be between 20 and 90 years old and have a confirmed diagnosis of moderate to severe shoulder osteoarthritis. Participants should be experiencing a minimum pain level of 4 out of 10. The study will only involve one shoulder for the injection, and participants will be randomly assigned to receive either Cingal or cortisone. Importantly, those with certain medical conditions or who have had specific treatments in the past months may not be eligible. Participants can expect to fill out questionnaires about their pain and treatment experience, and they will be contributing to important research that could help improve pain management for others in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • A clinical examination that confirms the radiological diagnosis of moderate to severe primary shoulder osteoarthritis, stage II and above, according to the Samilson-Prieto classification.
• • Patients aged between 20 and 90 years.
• • A patient with bilateral shoulder osteoarthritis will choose the side of the infiltration, only one side can be chosen to participate in the study.
• • The patient must have a clinical pain threshold of a minimum of 4/10 on the visual analogue scale.
• • The patient must have the cognitive ability to read and fill out the questionnaires.
• • The patient must be able to read and understand French or English
• Exclusion Criteria:
• • Presence of a transfixing rotator cuff tear assessed on MRI.
• • No previous shoulder reconstruction surgery.
• • Pregnant woman.
• • A patient who has received a cortisone infiltration within 6 months prior to the start of the study.
• • A patient who has received a platelet-rich plasma or a hyaluronic acid infiltration within 12 months prior to the start of the study.
• • Diagnosis of avascular necrosis.
• • Disease affecting the studied joint (systemic inflammatory disease, history of septic arthritis, osteonecrosis, etc.)
• • Suspicion or presence of active local infectious process.
• • Presence or suspicion of neoplasia or local metastasis.
• • Severe trauma to the shoulder ( ≤ 3 months)
• • Significant cognitive impairment or insufficient language proficiency to adequately answer the questionnaires.
• • Any other serious medical condition that does not allow participation in the study or may be a contraindication to cortisone injection.