Impact of Suture Type on Pigment Disturbances in Patients of Skin of Color
Launched by MELISSA PUGLIANO-MAURO · Jun 3, 2022
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at how the type of suture used during skin surgery affects the appearance of scars and skin color changes, specifically in patients with darker skin tones. Researchers want to find out if dissolvable sutures, which break down over time, work better than non-dissolvable sutures, which stay in the skin until they are removed. Patients who are eligible for this study are adults 18 years or older, who are having dermatologic surgery with a specific type of cut that is at least 3 cm long. They should also have skin color rated 4 or higher on a special scale that measures skin tone.
Participants in the trial will have each type of suture applied to different parts of their wound during surgery. Follow-up assessments will be done at various times after the procedure to check on the healing process and appearance of the scar. This study aims to improve cosmetic outcomes for patients with skin of color, helping to ensure the best possible results after surgery. If you meet the eligibility criteria and are interested in participating, you will need to provide consent and be able to return for follow-up visits.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Age 18 years or older
- • 2. Undergoing dermatologic surgery with planned standard elliptical excision with wound length of 3 cm or greater. Benign and malignant lesions will be included, including those that have undergone Mohs micrographic surgery prior to standard linear closure. All body sites will be included.
- • 3. Able to give informed consent
- • 4. Able to return for 3 month follow up
- • 5. New Immigration Scale (NIS) skin color 4 or greater - The NIS is an 11 point scale, ranging from zero to 10, with zero representing albinism and 10 representing the darkest possible skin.
- Exclusion Criteria:
- • 1. High-tension closures not amenable to 5-0 simple running epidermal sutures
- • 2. Known allergy to suture material
- • 3. Pregnant
About Melissa Pugliano Mauro
Melissa Pugliano-Mauro is a dedicated clinical trial sponsor with a focus on advancing innovative therapeutic solutions through rigorous research and development. With a strong background in clinical operations and regulatory compliance, she leads initiatives that prioritize patient safety and efficacy in treatment methodologies. Her commitment to fostering collaboration among multidisciplinary teams ensures the successful execution of clinical trials, driving progress in the field of medicine. Through a meticulous approach to study design and implementation, Melissa aims to contribute to the advancement of healthcare and improve outcomes for patients globally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Pittsburgh, Pennsylvania, United States
Pittsburgh, Pennsylvania, United States
Pittsburgh, Pennsylvania, United States
Patients applied
Trial Officials
Melissa Pugliano-Mauro, MD
Principal Investigator
University of Pittsburgh Medical Center
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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